Interacting with TRPC1 after Wounding
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چکیده
منابع مشابه
RhoA enhances store-operated Ca entry and intestinal epithelial restitution by interacting with TRPC1 after wounding
Chung HK, Rathor N, Wang SR, Wang JY, Rao JN. RhoA enhances store-operated Ca entry and intestinal epithelial restitution by interacting with TRPC1 after wounding. Am J Physiol Gastrointest Liver Physiol 309: G759–G767, 2015. First published September 3, 2015; doi:10.1152/ajpgi.00185.2015.—Early mucosal restitution occurs as a consequence of epithelial cell migration to resealing of superficial...
متن کاملRhoA enhances store-operated Ca2+ entry and intestinal epithelial restitution by interacting with TRPC1 after wounding.
Early mucosal restitution occurs as a consequence of epithelial cell migration to resealing of superficial wounds after injury. Our previous studies show that canonical transient receptor potential-1 (TRPC1) functions as a store-operated Ca(2+) channel (SOC) in intestinal epithelial cells (IECs) and plays an important role in early epithelial restitution by increasing Ca(2+) influx. Here we fur...
متن کاملSTIM1 translocation to the plasma membrane enhances intestinal epithelial restitution by inducing TRPC1-mediated Ca2+ signaling after wounding.
Early epithelial restitution is an important repair modality in the gut mucosa and occurs as a consequence of epithelial cell migration. Canonical transient receptor potential-1 (TRPC1) functions as a store-operated Ca2+ channel (SOCs) in intestinal epithelial cells (IECs) and regulates intestinal restitution, but the exact upstream signals initiating TRPC1 activation after mucosal injury remai...
متن کاملSTIM1 translocation to the plasma membrane enhances intestinal epithelial restitution by inducing TRPC1-mediated Ca signaling after wounding
Rao JN, Rathor N, Zou T, Liu L, Xiao L, Yu T, Cui Y, Wang JY. STIM1 translocation to the plasma membrane enhances intestinal epithelial restitution by inducing TRPC1-mediated Ca signaling after wounding. Am J Physiol Cell Physiol 299: C579–C588, 2010. First published July 14, 2010; doi:10.1152/ajpcell.00066.2010.—Early epithelial restitution is an important repair modality in the gut mucosa and...
متن کاملCaveolin‐1 enhances rapid mucosal restitution by activating TRPC1‐mediated Ca2+ signaling
Early rapid mucosal restitution occurs as a consequence of epithelial cell migration to reseal superficial wounds, a process independent of cell proliferation. Our previous studies revealed that the canonical transient receptor potential-1 (TRPC1) functions as a store-operated Ca(2+) channel (SOCs) in intestinal epithelial cells (IECs) and regulates epithelial restitution after wounding, but th...
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